Ibutamoren MK-677 Powder, CAS NO.: 15972-10-0
Introduction:
Product Name: Ibutamoren mesylate,MK-677,mk677,sarms
CAS:159752-10-0
Mf:C27h36n4o5s.CH4o3s
MW:624.776
Appearance:Powder
Putity:99% Min.
Application: Pharmaceutical raw materials
Description
Ibutamoren mesylate (MK-677) is an active nonpeptide growth hormone (GH) secretagogue.
IC50 Value:
Target: GHSR
Ibutamoren mesylate (MK-677) stimulates GH release through a pituitary and hypothalamic receptor that is different from the G H-releasing hormone receptor. MK-677is a item which acts as a potent, active gh secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including gh and I G F-1, but without affecting cortisol levels. It is currently under development as a potential treatment for reduced levels of these hor m ones, such as in gh deficient children or elderly adults, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. Ibutamoren mesylate (MK-0677) also alters metabolism of body fat and so may have application in the treatment of obesity.
Application area
An experimental meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARd agonist. Exhibits selectivity for PPARd compared t
Usage An experimental meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
Ibutamoren Mesylate Usage
An experimental item meant to control lipids and increase the level of HDL, or good cholesterol, in the
bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARd agonist. Exhibits selectivity for
PPARd compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear
receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
Ibutamoren Mesylate Benefits
the subjects showed a sustained increase in serum concentration of I GF-1 and
Growth Hormone; in addition, the nitrogen wasting was reversed, showing great potential for treatment of conditions involving muscle wasting.
A study done for the treatment of osteoporosis and bone mineral density showed some increase in bone density, so there is a true impact on bone mineral density. This can help with injury recovery during your cycle.
Analysis
Package
Small order: packed with aluminum seal bag, 10g, 100g, 1kg
Large order: packed with drum, 25kg/drum
Bodybuilding Raw Material Powder Ibutamoren Mesylate Mk-677